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NFL best bets for Week 15: Broncos will keep it low-scoring vs. Colts

The Buffalo Bills scored six offensive touchdowns (three rushing and three passing) and didn’t turn the ball over in Sunday’s 44-42 loss at the Los Angeles Rams. Up until that point, teams with those stats were 41-0 in the Super Bowl era (including the playoffs), with all of them winning by at least seven points. Yet Buffalo couldn’t cover a 4½-point spread, putting another loss on my ledger.

I shouldn’t complain too much, as chaos helped us cover our bet on the Cincinnati Bengals -5½ against the Dallas Cowboys. The score was tied at 20 at the two-minute warning, with Dallas set to get the ball back after a blocked punt, but Amani Oruwariye was unable to secure the ball and Cincinnati regained possession. Ja’Marr Chase’s ensuing touchdown catch secured us a winning wager.

Best bets record in 2024: 9-22

Los Angeles Rams at San Francisco 49ers (-2½)

Thursday, 8:15 p.m. | Prime Video

Pick: 49ers -2½

The Rams are coming off that big win against the Bills but find themselves as the underdog again on short rest. These situations have not proved fruitful for the team catching points again on Thursday nights. Since 2002, teams in this situation are 13-22 against the spread and miss covering by almost three points per game, per TruMedia. With the spread already under the key number of three, I am comfortable backing San Francisco. Teams like the Rams are also a paltry 8-27 straight-up over that span in these situations, making the 49ers money line look enticing, too.

Indianapolis Colts at Denver Broncos (-3½)

Sunday, 4:25 p.m. | CBS

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Pick: Under 45 points (The pick is Broncos -3½, but it is not a best bet)

The Broncos are one of the best defensive teams in the NFL. Opponents are scoring almost eight fewer points per game against them after accounting for the down, distance and field position of each play, per TruMedia. Aaron Schatz’s defense-adjusted value over average agrees and ranks their defense fifth overall after adjusting their efficiency for strength of schedule.

Plus, when two teams coming off a bye meet in a game with a total greater than 40, the under has cashed almost 60 percent of the time since 2002, per TruMedia. Over this year and last year, the under is 12-0. In a game that could prove pivotal for playoff positioning, I like the under.

The plays above represent our best bets of the week because our analysis shows their value is the most lucrative compared with what we expect to happen on the field. Below, you will find against-the-spread picks for all of the games on this week’s schedule.

However, trying to pick every game is something of a fool’s errand. The house wins so often partly because bettors try to make too many plays when the odds aren’t in their favor. Keep that in mind when evaluating the remaining games from this week’s schedule.

Baltimore Ravens (-14½) at New York Giants

Sunday, 1 p.m. | CBS

Pick: Giants +14½

Dallas Cowboys at Carolina Panthers (-2½)

Sunday, 1 p.m. | Fox

Pick: Panthers -2½

Kansas City Chiefs (-4½) at Cleveland Browns

Sunday, 1 p.m. | CBS

Pick: Chiefs -4½

Cincinnati Bengals (-4½) at Tennessee Titans

Sunday, 1 p.m. | Fox

Pick: Bengals -4½

Miami Dolphins at Houston Texans (-2½)

Sunday, 1 p.m. | CBS

Pick: Texans -2½

New York Jets (-3½) at Jacksonville Jaguars

Sunday, 1 p.m. | Fox

Pick: Jaguars +3½

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Washington Commanders (-7) at New Orleans Saints

Sunday, 1 p.m. | Fox

Pick: Commanders -7

Tampa Bay Buccaneers at Los Angeles Chargers (-3)

Sunday, 4:25 p.m. | Fox

Pick: Buccaneers +3

Pittsburgh Steelers at Philadelphia Eagles (-5½)

Sunday, 4:25 p.m. | Fox

Pick: Eagles -5½

New England Patriots at Arizona Cardinals (-5½)

Sunday, 4:25 p.m. | CBS

Pick: Cardinals -5½

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Buffalo Bills at Detroit Lions (-1½)

Sunday, 4:25 p.m. | CBS

Pick: Lions -1½

Green Bay Packers (-2½) at Seattle Seahawks

Sunday, 8:20 p.m. | NBC

Pick: Packers -2½

Chicago Bears at Minnesota Vikings (-7)

Monday, 8 p.m. | ABC

Pick: Vikings -7

Atlanta Falcons (-4½) at Las Vegas Raiders

Monday, 8:30 p.m. | ESPN

Pick: Falcons -4½

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